Two Months In: Strong Growth From Nuvation Bio and Caris Life Sciences
For the past two months, I've been invested in Nuvation Bio and Caris Life Sciences. Their stock prices have performed very well.
Moc
prieš 5 mėnesius
NUVB reported preliminary net product revenue of $24.7 million for IBTROZI since launch
Nuvation Bio Inc. (NUVB) reported preliminary net product revenue of $24.7 million for IBTROZI since its launch in June 2025, with fourth quarter revenue reaching $15.7 million.
The company said 432 patients started treatment on IBTROZI for advanced ROS1-positive non-small cell lung cancer since the drug’s launch, with 216 new patients beginning treatment in the fourth quarter. The treatment adoption rate is approximately six times greater than prior ROS1 tyrosine kinase inhibitor launches based on IQVIA data, according to the company.
Nuvation Bio received a $25 million milestone payment from Nippon Kayaku in the fourth quarter following establishment of a reimbursement price in Japan. The company reported preliminary cash, cash equivalents and marketable securities of approximately $529.2 million as of December 31, 2025.
On January 11, 2026, the company entered an exclusive license and collaboration agreement with Eisai Co., Ltd. to develop, register and commercialize taletrectinib for ROS1-positive non-small cell lung cancer in Europe, the Middle East, North Africa, Russia, Turkey, Canada, Australia, New Zealand, Singapore, the Philippines, Indonesia, Thailand, Malaysia, Vietnam and India.
IBTROZI received FDA approval on June 11, 2025, for treating adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer following Priority Review and Breakthrough Therapy designations.
The company plans to continue enrollment of its phase 3 study evaluating safusidenib in high-grade and high-risk IDH1-mutant gliomas and pursue business development opportunities to expand its pipeline.
The preliminary financial results are subject to adjustment pending completion of the company’s financial closing procedures. Nuvation Bio expects to issue full financial results for the fourth quarter and full year 2025 in March 2026.
Moc
prieš 7 mėnesius
Good news
$NUVB announced the publication of positive Phase 2 study results for safusidenib in treating grade 2 IDH1-mutant glioma patients. The findings were published in the journal Neuro-Oncology on November 8.
The study evaluated 27 patients with IDH1-mutant grade 2 gliomas who had received no prior anticancer therapy except for resection or biopsy. The trial met its primary endpoint with an objective response rate of 44.4%. At 24 months, 87.9% of patients remained progression-free.
Median progression-free survival had not been reached as of the March 10, 2023 data cutoff, with a median follow-up time of 28 months. The median duration of response could not be estimated because no progression events had occurred.
Adverse events were described as mostly mild to moderate. Grade 3 or greater treatment-related adverse events occurred in five patients (18.5%). Three patients discontinued treatment due to adverse events, two of which investigators considered related to safusidenib.
The company noted that a Good Clinical Practice noncompliance issue regarding adverse event collection was identified during the study. Safety data was subsequently re-investigated and re-collected according to study protocol.
Safusidenib is an oral, brain-penetrant inhibitor of mutant IDH1. Nuvation Bio is progressing the ongoing G203 study in high-grade IDH1-mutant gliomas, with a protocol amendment planned to finalize the study as a global Phase 3 trial to support potential regulatory approvals.
The company stated that as of September 15, 2025, 12 patients remained on treatment with safusidenib. Gliomas are the most common type of brain cancer in adults, with nearly 2,400 people diagnosed with IDH1-mutant gliomas annually in the United States.
BailyW
prieš 7 mėnesius
Up?
Has this got anymore juice? Holding nicely. What do people think?
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Įvertinta 4,6/5, remiantis 95 591 atsiliepimais apie
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Įvertinta 4,6/5, remiantis 95 591 atsiliepimais apie
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Love the Trading 212 App it’s great fun…
Love the Trading 212 App it’s great fun to use and it’s really intuitive in helping you to monitor your investments as they grow!
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Safe,simple and easy
Great website, easy to use. Regular updates. Sit back and do nothing. Couldn’t be simpler. Very happy.
Pakviestas
Great app and easy to use
The Trading 212 app is easy to use and I like the fact you can see your investment grow on a daily basis.
Pakviestas
Very easy account making/saving…
It’s been so easy to create accounts and start investing/saving would recommend to anyone
Pakviestas
Best app
This investment app is very easy to use and has a user-friendly interface. I feel confident knowing my money is secure, and the investment process is simple and straightforward. The customer support is also responsive and helpful whenever needed. Highly recommended for anyone looking for a reliable investment platform!
Pakviestas
Easy and stress free
Investing is made very easy with Trading 212.
Pakviestas
Easy to use
Easy to set up easy to use deposit and take out
Pakviestas
The best trading app out there
The best trading app out there. No question
Pakviestas
Easy to use
Easy to use. I love it
Pakviestas
Low fees ETFs + on of the best interest…
Low fees ETFs + on of the best interest rate on cash attached
Pakviestas
Easy to use
Easy to use, recommend if you’re interested in investing
Pakviestas
Very helpful and professional and my…
Very helpful and professional and my query was dealt with quickly and efficiently.
Pakviestas
All good!
Till now, almost a year after start using it, the experience has been going very well. No issues with any of the activities I needed to perform, friendly user interface and enough tools. I'm also glad that looks like the team ears the community. Keep up the good work.
Pakviestas
A great platform to invest
A great platform to invest. The app is easy to navigate. Easy to transfer money.
Used stocks and shares ISA as well as…
Used stocks and shares ISA as well as Cash ISA.
Like the stocks interface, info about financials of the companies. It does not work very reliably on niche stocks or ETFs, but I would be surprised if it did.
Also it tracks the ISA limits, ISAs are flexible. So can take money in and out all the time. Withdrawals are very quick. They tell it may take few businesses days, but usually goes through in a few minutes (if not seconds).
Cash ISA interest was high, not it is not really, but I suppose it is a price for ability to withdraw anytime.
It would be nice if I could buy government bonds there as stocks and shares ISA product.
Pakviestas
Great experience.
Orders execution is really smooth, level of transparency is amazing when it comes to clear track of transactions and pies is very helpful.
If they just can enable higher freedom when it comes to communication between members in one community/pie, it will be amazing.
Pakviestas
Great app
Great app. Very easy to use. No complications atall
Pakviestas
Great even for beginners
Really easy to use and track investments. Fees are clear and fair.
The ability to communicate with other investors for support is a good feature, especially for beginners.
I'm a newbie to stocks and shares, this app has been perfect to learn with as well as actual investments.
Pakviestas
T212 - The SIPP’er heros.
The Trading 212 team pretty much does all the heavy lifting when setting up a SIPP, you do need to supply the obvious details, and will most likely need to respond to your previous pension provider to confirm your sure with the transfer. But as far as pension pot transfers go, T212 is fantastic! They looked into potential loss of protected terms and brought this up quickly for me to make a decision. The response time from the team is really quick and professional- I cant recommend them enough. I also really like the SIPP interface on the app, its really easy to understand and is seamless with your other investment accounts. 10/10.
Pakviestas
Great site makes investing very easy…
Great site makes investing very easy and exciting, still a little confused on some things but getting there, thanks
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Dažniausiai užduodami klausimai
Kokia yra Nuvation Bio (NUVB) akcijos kaina?
Dabartinė Nuvation Bio (NUVB) kaina yra 6 $.
Koks yra NUVB52 savaičių maksimumas?
52 savaičių maksimumas NUVB yra 9,78 $.
Koks yra NUVB 52 savaičių žemiausias lygis?
52 savaičių žemiausias NUVB kursas yra 1,78 $.
Koks yra NUVB savaitės rezultatas?
Per pastarąją savaitę NUVB kaina pasikeitė 17,19 %.
Koks yra NUVB mėnesio našumas?
Per pastarąjį mėnesį NUVB kaina pasikeitė 27,12 %.
Koks yra NUVB 3 mėnesių rezultatas?
Per pastaruosius tris mėnesius NUVB kaina pasikeitė 42,18 %.
Koks yra NUVB 6 mėnesių rezultatas?
Per pastaruosius šešis mėnesius NUVB kaina pasikeitė −37,11 %.
Koks yra NUVBmetinis našumas?
Per pastaruosius metus NUVB kaina pasikeitė 204,57 %.